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Reduction of Total Parenteral Nutrition‐Induced Urinary Calcium Loss by Increasing the Phosphorus in the Total Parenteral Nutrition Prescription
Author(s) -
Wood Richard J.,
Sitrin Michael D.,
Cusson Gilbert J.,
Rosenberg Irwin H.
Publication year - 1986
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607186010002188
Subject(s) - parenteral nutrition , hypercalciuria , calcium , medicine , phosphorus , urinary calcium , urinary system , excretion , endocrinology , chemistry , organic chemistry
Hypercalciuria and negative calcium balance are potential complications of total parenteral nutrition (TPN). Dietary phosphorus has been observed to have an hypocalciuretic effect. The present study evaluates the effects of administration of increasing intravenous phosphorus (P) loads on urinary calcium excretion in TPN patients. Urinary calcium exceeded daily calcium intake by 50 mg/d when 700 mg/d P was administered, was equal to intake at 1000 mg/d P, and was 30 mg/d less than calcium intake when 1300 mg/d P was given. These findings suggest that TPN‐induced hypercalciuria can be attenuated in the short‐term by intravenous phosphate. Reevaluation of the phosphorus requirement in patients receiving long‐term TPN should be considered. (Journal of Parenteral and Enteral Nutrition 10:188–190, 1986)