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Serum Vitamin E Levels in Very Low‐Birth Weight Infants Receiving Vitamin E in Parenteral Nutrition Solutions
Author(s) -
Devito Victoria,
Reynolds John W.,
Benda Gerda I.,
Carlson Christina
Publication year - 1986
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/014860718601000163
Subject(s) - parenteral nutrition , multivitamin , medicine , low birth weight , enteral administration , birth weight , gestational age , vitamin , retinopathy of prematurity , vitamin e , incidence (geometry) , pediatrics , gastroenterology , pregnancy , biochemistry , chemistry , biology , physics , optics , genetics , antioxidant
Serum vitamin E levels were measured in 17 very low‐birth weight infants in the first 2 wk of life, before and after the institution of intravenous vitamin E supplementation in a dosage of 4.5 mg/day, as a component of MVI Pediatric multivitamin preparation. Serum vitamin E levels were 0.22 ± 0.16 (SD) mg/dl before supplementation, and rose to 2.55 ± 0.65 (SD) mg/dl in nine infants more than 899 g birth weight, and rose to 3.68 ± 0.70 (SD) mg/dl in six infants less than 900 g at birth. These postsupplementation serum vitamin E levels are in the range in which a reduction of incidence or severity of retinopathy of prematurity and intraventricular cerebral hemorrhage has been reported by others. No toxic effects of the preparation or of the increased vitamin E levels were found. ( Journal of Parenteral and Enteral Nutrition 10: 63–65, 1986)