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Shoshin Beriberi: An Unusual Complication of Prolonged Parenteral Nutrition
Author(s) -
La Selve P.,
Demolin P.,
Holzapfel L.,
Blanc P.L.,
Teyssier G.,
Robert D.
Publication year - 1986
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607186010001102
Subject(s) - parenteral nutrition , medicine , beriberi , complication , anuria , malnutrition , thiamine , vitamin , lactic acidosis , surgery , intensive care medicine
After 4 weeks of total parenteral nutrition (TPN), a 12‐yr‐old girl exhibited an acute heart failure with high cardiac output, anuria, and severe lactic acidosis. The clinical, hemodynamic, and biological data suggested the diagnosis of shoshin beriberi which was proved by the low erythrocyte transketolase activity with elevated “TPP effect” and by the dramatic improvement of the patient after thiamin administration. Thiamin deficiency and severe neurological disorders have been described during long‐term parenteral nutrition. To our knowledge, this is the first report of the cardiovascular complication of this vitamin deprivation in long‐term TPN. ( Journal of Parenteral and Enteral Nutrition 10: 102–103,1986)