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Stability of the B Vitamins in Mixed Parenteral Nutrition Solution
Author(s) -
Chen Marianne F.,
Worth Boyce H.,
Triplett Linda
Publication year - 1983
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607183007005462
Subject(s) - parenteral nutrition , riboflavin , pyridoxine , enteral administration , sunlight , chemistry , vitamin , medicine , food science , biochemistry , physics , astronomy
The effects of various light conditions such as fluorescent light, and indirect and direct sunlight on the stability of the water‐soluble B vitamins in parenteral mixtures were studied. The levels of the B vitamins were determined by microbiologic assays and spectrophotometrically. Most of the B vitamins were found to be stable. However, indirect and direct sunlight destroyed 47 and 100%, respectively, of riboflavin‐5‐phosphate in eight hours. Direct sunlight destroyed 86% of pyridoxine HCl. There was no loss of folic acid in parenteral nutrition mixtures after storage for 7 wk. The microbiologic assays were found to be reliable to measure the levels of the B vitamins in parenteral nutrition solution. ( Journal of Parenteral and Enteral Nutrition 7 :462–464, 1983)