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Supplementation of Total Parenteral Nutrition Solutions with Ferrous Citrate
Author(s) -
Sayers Merlin H.,
Johnson David K.,
Schumann Louis A.,
Ivey Marianne F.,
Young Jeffry H.,
Finch Clement A.
Publication year - 1983
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607183007002117
Subject(s) - parenteral nutrition , ferrous , transferrin , liter , medicine , ferrous sulphate , chemistry , inorganic chemistry , organic chemistry
Daily infusion of a total parenteral nutrition (TPN) formulation containing 1 liter of 5.5% Travasol provides less than 0.1 milligrams of iron. By comparison, a formulation which includes a liter of 10% Travamin provides 2 milligrams of iron per day. To meet iron requirements in patients infusing formulations containing Travasol, iron was added as ferrous citrate. In in vitro experiments, 74% of this iron was available to transferrin. In seven patients in whom in vivo availability was tested by red cell incorporation, the mean availability was 81%. Ferrous citrate is recommended as a safe, effective additive to TPN solutions for adult patients requiring iron supplements.