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Selenium and Vitamin E Sufficiency in Premature Infants Requiring Total Parenteral Nutrition
Author(s) -
Huston Robert K.,
Benda Gerda I.,
Carlson Christina V.,
Shearer Thomas R.,
Reynolds John W.,
Neerhout Robert C.
Publication year - 1982
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607182006006507
Subject(s) - parenteral nutrition , medicine , regimen , vitamin e , lipid peroxide , selenium , thiobarbituric acid , vitamin , antioxidant , gastroenterology , lipid peroxidation , chemistry , biochemistry , oxidative stress , organic chemistry
A randomized prospective study of LBW infants was undertaken to evaluate the effect of parenteral lipid infusions upon their antioxidant systems. Ten babies received a parenteral nutrition regimen with lipid emulsion, and ten received a regimen without lipid. Although the addition of lipid emulsion to the total parenteral nutrition regimen led to a rise in vitamin E levels, the selenium levels fell in both groups. Neither group showed evidence of deficient antioxidant systems by the peroxide hemolysis test or thiobarbituric acid test. There did not seem to be any adverse effect of the lipid infusion upon the clinical course of the infants except for hyperlipidemia. There was a better weight gain in infants receiving lipid.