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An Evaluation of the Diurnal Rhythm of Urea Excretion in Healthy Young Adults
Author(s) -
Steffee William P.,
Anderson Carl F.,
Young Ver R.
Publication year - 1981
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607181005005378
Subject(s) - excretion , urea , rhythm , urine , circadian rhythm , medicine , persistence (discontinuity) , endocrinology , urea nitrogen , endogeny , urea cycle , physiology , diurnal temperature variation , zoology , biology , creatinine , biochemistry , amino acid , geotechnical engineering , arginine , atmospheric sciences , engineering , geology
A diurnal variation in urine urea excretion has been documented to exist in healthy young adults. Its persistence when dietary nitrogen intake approaches zero suggests that influences other than diet may in part generate the rhythm. These may include variations in the efficiency of rates of endogenous protein turnover or perhaps changes in renal tubular handling of urea especially in states of dietary nitrogen inadequacy. Recognition of these effects in the normal state are important before ascribing importance to changes in the disease state, particularly as we gain the ability to intervene nutritionally in the hospital setting.