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Candida Endophthalmitis Associated With Total Parenteral Nutrition
Author(s) -
Nahata Milap C.,
Davidorf Frederick H.,
Caldwell James H.,
Weiss Ester T.
Publication year - 1981
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607181005002150
Subject(s) - vitrectomy , pars plana , amphotericin b , endophthalmitis , medicine , parenteral nutrition , candida albicans , surgery , antifungal , mycosis , dermatology , visual acuity , microbiology and biotechnology , biology
Candida albicans is the most common fungal infection which can occur in patients receiving total parenteral nutrition therapy. While rare, Candida endophthalmitis also can occur and must be considered as a potential risk of this treatment. Early detection and management of this disorder can alter the visual outcome for these patients. Systemic administration of amphotericin B and fluocytosine is the most common form of treatment for Candida endophthalmitis. In cases not responsive to systemic administration of antifungal agents, surgical management through pars plana vitrectomy can potentially eradicate the infection and preserve vision. We present a case of bilateral Candida endophthalmitis treated with amphotericin B and fluocytosine, and also with pars plana vitrectomy with the intracameral injection of amphotericin B into the anterior vitreous cavity. Systemic and intracameral use of antifungal drug therapy combined with vitrectomy restored useful vision to the patient.