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Pediatric TPN: Efficacy and Toxicity of a New Fat Emulsion
Author(s) -
Connors Robert H.,
Coran Arnold G.,
Wesley John R.
Publication year - 1980
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/014860718000400409
Subject(s) - parenteral nutrition , fat emulsion , calorie , medicine , isotonic , enteral administration , emulsion , toxicity , fish oil , caloric intake , intensive care medicine , chemistry , body weight , fish <actinopterygii> , biology , biochemistry , fishery
Fat emulsions are particularly valuable in pediatric total parenteral nutrition (TPN) because they provide an isotonic solution rich in calories. Little is known about the ideal composition of fatty acid emulsions, however, and very few formulations are commercially available. A new fat emulsion using a safflower oil base has recently been approved. We have used this new emulsion to provide a significant percentage of the nonprotein caloric requirements (24 to 42%) in 4 patients requiring TPN. These patients ranged in age from 1 to 15 years and received no enteral nutrition during the 3‐week course of the study. Nutritional improvement without major toxic effects was documented in each patient.