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Effect of Intravenous Infusion Solutions on Bioelectrical Impedance Spectroscopy
Author(s) -
Yap Jason,
Rafii Mahroukh,
Azcue Maria,
Pencharz Paul
Publication year - 2017
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607115619598
Subject(s) - bioelectrical impedance analysis , saline , medicine , anesthesia , body water , body weight , body mass index
Background: Bioelectrical impedance (BIA) is often used to measure body fluid spaces and thereby body composition. However, in acute animal studies, we found that impedance was driven by the saline content of intravenous (IV) fluids and not by the volume. The aim of the study was to investigate the effect of 3 different fluids acutely administered on the change in impedance, specifically resistance (R). Materials and Methods : Nine healthy adults participated in 3 treatment (0.9% saline, 5% dextrose, and a mixture of 0.3% saline + 3.3% dextrose) experiments on nonconsecutive days. They all received 1 L of one of the treatments intravenously over a 1‐hour period. Repeated BIA measurements were performed prior to IV infusion and then every 5 minutes for the 1‐hour infusion period, plus 3 more measurements up to 15 minutes after the completion of the infusion. Results : The change in R in the 0.9% saline infusion experiment was significantly lower than that of the glucose and mixture treatment ( P < .001). Conclusion : Bioelectrical impedance spectroscopy and BIA measure salt rather than the volume changes over the infusion period. Hence, in patients receiving IV fluids, BIA of any kind (single frequency or multifrequency) cannot be used to measure body fluid spaces or body composition.