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Nutrition Support and Infections Associated With Hepatic Resection and Liver Transplantation in Patients With Chronic Liver Disease
Author(s) -
Masuda Toshiro,
Shirabe Ken,
Yoshiya Shohei,
Matono Rumi,
Morita Kazutoyo,
Hashimoto Naotaka,
Ikegami Toru,
Yoshizumi Tomoharu,
Baba Hideo,
Maehara Yoshihiko
Publication year - 2013
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607112456041
Subject(s) - medicine , parenteral nutrition , synbiotics , liver transplantation , perioperative , ascites , gastroenterology , enteral administration , transplantation , cirrhosis , malnutrition , immune system , liver disease , chronic liver disease , intensive care medicine , surgery , immunology , biology , probiotic , bacteria , genetics
Malnutrition is common in liver cirrhotic patients who will undergo liver resection or liver transplantation. A precise evaluation of their nutrition status is thus difficult because of the presence of ascites and the edema caused by their impaired protein synthesis. Both perioperative enteral and parenteral nutrition have benefits in reducing the morbidity and mortality of liver surgery, and in general, oral nutrition supplements are recommended. Branched‐chain amino acids (BCAAs) promote protein and glycogen synthesis and regulate immune system function. Synbiotics, a combination of pro‐ and prebiotics, is reported to enhance immune responses. Oral nutrition support with BCAAs, synbiotics, and an immune‐enhancing diet have a beneficial effect on preventing the perioperative infections associated with hepatic resection or liver transplantation.