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Hypercalcemia and Peptic Ulcer Disease–Related Milk‐Alkali Syndrome
Author(s) -
Grundfast Matthew B.,
Still Christopher D.,
Komar Michael J.
Publication year - 2003
Publication title -
nutrition in clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.725
H-Index - 71
eISSN - 1941-2452
pISSN - 0884-5336
DOI - 10.1177/0115426503018003250
Subject(s) - medicine , peptic ulcer , disease , histamine , calcium , gastroenterology , peptic , osteoporosis , proton pump inhibitor , reflux , histamine h2 receptor , receptor , antagonist
Milk‐alkali syndrome was considered “extinct” by 1985 because of the advent of non‐alkaline ulcer medications (ie, histamine‐2 receptor blockers and proton pump inhibitors). At that time, it was thought to cause<1% of hypercalcemia, which occurred when one ingested a sufficient quantity of calcium and alkali together. This case emphasizes the importance of considering this syndrome in patients who self‐medicate for control of symptoms related to gastroesophageal reflux and peptic ulcer disease and for those using calcium supplementation for prevention or treatment of osteoporosis.