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The Utility of Pharmacokinetics to the Pharmaceutical Industry
Author(s) -
NELSON ROBERT L.
Publication year - 1976
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1177/009127007601601018
Subject(s) - pharmacokinetics , pharmaceutical industry , pharmacology , clinical pharmacology , drug , medicine , clinical trial , drug development , pharmaceutical sciences , intensive care medicine
Pharmacokinetic studies done early in the course of drug development can favorably influence the course of research by suggesting optimum dosage regimens, drug delivery methods, and fixed-ratio combinations and by alerting the clinical pharmacologist to potential problems. Pharmacokinetic data can be useful in the design of rational clinical drug research and thereby expedite clinical trials and save research costs. Thus, in addition to their value in the area of comparative bio-availability, pharmacokinetic studies carried out by the pharmaceutical industry are useful economically as well as scientifically.