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Baclofen‐Induced Morbiliform Rashes: A Case series
Author(s) -
Saddichha Sahoo,
Jayaram Naveen,
Manjunatha Narayana,
Benegal Vivek
Publication year - 2011
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1177/0091270010385936
Subject(s) - baclofen , spasticity , medicine , agonist , adverse effect , pharmacology , anesthesia , receptor
Baclofen is a gamma amino butyric acid (GABA) derivative that is a specific agonist at GABA‐B receptors. Initially used in the treatment of spasticity, it is now being used in the treatment of alcohol dependence. Although it has several known adverse effects, incidence of rashes developing due to baclofen is very rare, and morbiliform rashes due to baclofen, an exceedingly rare adverse effect, has been reported only once before. We report a case series of 4 patients who developed morbiliform rashes after initiation of baclofen.