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Longitudinal changes in the antecedent and early manifest course of bipolar disorder—A narrative review of prospective studies
Author(s) -
Andrea Pfennig,
Karolina Leopold,
Philipp Ritter,
Anne Böhme,
Emanuel Severus,
Michael Bauer
Publication year - 2017
Publication title -
australian and new zealand journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.66
H-Index - 116
eISSN - 1440-1614
pISSN - 0004-8674
DOI - 10.1177/0004867417700730
Subject(s) - bipolar disorder , temperament , psychology , psychopathology , clinical psychology , anxiety , mania , prospective cohort study , mood , cognition , developmental psychology , psychiatry , personality , medicine , social psychology
Prospective study designs ideally allow patients to be followed from the first manifestations of the illness or even from an at-risk stage. It can thus provide data on the predictive value of changes in clinical symptomatology, cognition or further biological markers to broaden our understanding of the etiopathology and symptomatic trajectory of bipolar disorders. The scope of this narrative review is to summarize evidence from prospectively collected data on psychopathological and other clinical and biological changes in the early developmental course of bipolar disorders.

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