Metabolomic Expression of Laryngeal and Hindlimb Muscles in Adult versus Senescent Rats | Zendy

Adrianna C. Shembel | Zendy; Yik Siu | Zendy; Tenzin Lhakhang | Zendy; Leonard J. Ash | Zendy; Drew R. Jones | Zendy; Aaron M. Johnson | Zendy

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Metabolomic Expression of Laryngeal and Hindlimb Muscles in Adult versus Senescent Rats

Author(s) -

Adrianna C. Shembel,

Yik Siu,

Tenzin Lhakhang,

Leonard J. Ash,

Drew R. Jones,

Aaron M. Johnson

Publication year - 2021

Publication title -

annals of otology rhinology and laryngology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.65

H-Index - 91

eISSN - 1943-572X

pISSN - 0003-4894

DOI - 10.1177/00034894211014692

Subject(s) - hindlimb , metabolite , metabolome , larynx , metabolomics , skeletal muscle , leg muscle , biology , anatomy , endocrinology , medicine , bioinformatics , physical medicine and rehabilitation

(1) Determine the feasibility of obtaining a global, unbiased metabolomic profile on laryngeal muscle in a rat model; (2) evaluate the impact of biological aging on the laryngeal metabolome; and (3) characterize biochemical expression differences between aged and non-aged laryngeal and hindlimb muscle.

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