Open AccessEvidence for Use of Cannabinoids in Mood Disorders, Anxiety Disorders, and PTSD: A Systematic Review
Author(s) -
Corneliu N. Stanciu,
Mary F. Brunette,
Nikhil Teja,
Alan J. Budney
Publication year - 2021
Publication title -
psychiatric services
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.517
H-Index - 145
eISSN - 1557-9700
pISSN - 1075-2730
DOI - 10.1176/appi.ps.202000189
Subject(s) - anxiety , cannabidiol , psychiatry , social anxiety , mood , cannabis , mood disorders , randomized controlled trial , anxiety disorder , psychology , depression (economics) , clinical psychology , medicine , economics , macroeconomics
Two primary compounds of the cannabis plant ( Cannabis sativa ), delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), differentially and dose-dependently affect mood and anxiety. In this systematic review, the authors summarize the design and results of controlled trials assessing the effects of THC and CBD on affective disorders, anxiety disorders, and posttraumatic stress disorder (PTSD).