Open AccessEfficacy of Combining Varenicline and Naltrexone for Smoking Cessation and Drinking Reduction: A Randomized Clinical Trial
Author(s) -
Lara A. Ray,
ReJoyce Green,
Craig K. Enders,
Adam M. Leventhal,
Erica N. Grodin,
Gang Li,
Aaron C. Lim,
Emily E. Hartwell,
Alex Venegas,
Lindsay R. Meredith,
Steven J. Nieto,
Steven Shoptaw,
Daniel W. C. Ho,
Karen Miotto
Publication year - 2021
Publication title -
the american journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.477
H-Index - 353
eISSN - 1535-7228
pISSN - 0002-953X
DOI - 10.1176/appi.ajp.2020.20070993
Subject(s) - varenicline , smoking cessation , medicine , naltrexone , abstinence , placebo , randomized controlled trial , nicotine , anesthesia , psychiatry , opioid , receptor , alternative medicine , pathology
Pharmacological treatments that can concomitantly address cigarette smoking and heavy drinking stand to improve health care delivery for these highly prevalent co-occurring conditions. This superiority trial compared the combination of varenicline and naltrexone against varenicline alone for smoking cessation and drinking reduction among heavy-drinking smokers.