Open AccessDistinct Symptom-Specific Treatment Targets for Circuit-Based Neuromodulation
Author(s) -
Shan Siddiqi,
Stephan F. Taylor,
Danielle Cooke,
Álvaro PascualLeone,
Mark S. George,
Michael Fox
Publication year - 2020
Publication title -
the american journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.477
H-Index - 353
eISSN - 1535-7228
pISSN - 0002-953X
DOI - 10.1176/appi.ajp.2019.19090915
Subject(s) - anhedonia , deep brain stimulation , connectome , depression (economics) , neuromodulation , psychology , anxiety , brain stimulation , randomized controlled trial , transcranial magnetic stimulation , human connectome project , stimulation , neuroscience , medicine , psychiatry , functional connectivity , disease , parkinson's disease , dopamine , economics , macroeconomics
Treatment of different depression symptoms may require different brain stimulation targets with different underlying brain circuits. The authors sought to identify such targets, which could improve the efficacy of therapeutic brain stimulation and facilitate personalized therapy.