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Genetics of Recurrent Early-Onset Major Depression (GenRED): Significant Linkage on Chromosome 15q25-q26 After Fine Mapping With Single Nucleotide Polymorphism Markers
Author(s) -
Douglas F. Levinson,
Oleg V. Evgrafov,
James A. Knowles,
James B. Potash,
Myrna M. Weissman,
William A. Scheftner,
J. Raymond DePaulo,
Raymond R. Crowe,
Kathleen P. Murphy-Eberenz,
Diana H. Marta,
Melvin G. McInnis,
Philip Adams,
Madeline Gladis,
Erin B. Miller,
J. Regan Thomas,
Peter Holmans
Publication year - 2007
Publication title -
american journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.477
H-Index - 353
eISSN - 1535-7228
pISSN - 0002-953X
DOI - 10.1176/ajp.2007.164.2.259
Subject(s) - genetics , linkage disequilibrium , single nucleotide polymorphism , locus (genetics) , biology , haplotype , microsatellite , genetic linkage , snp , snp genotyping , allele , genotype , gene
The authors studied a dense map of single nucleotide polymorphism (SNP) DNA markers on chromosome 15q25-q26 to maximize the informativeness of genetic linkage analyses in a region where they previously reported suggestive evidence for linkage of recurrent early-onset major depressive disorder.

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