Open AccessThe NEI Audacious Goals Initiative: Advancing the Frontier of Regenerative Medicine
Author(s) -
Steven Becker,
Santa J. Tumminia,
Michael F. Chiang
Publication year - 2021
Publication title -
translational vision science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 21
ISSN - 2164-2591
DOI - 10.1167/tvst.10.10.2
Subject(s) - regenerative medicine , retinal pigment epithelium , neuroscience , clinical trial , retinal , frontier , optometry , medicine , ophthalmology , political science , biology , stem cell , pathology , microbiology and biotechnology , law
Eight years since the launch of the National Eye Institute Audacious Goals Initiative for Regenerative Medicine, real progress has been made in the effort to restore vision by replacing retinal neurons. Although challenges remain, the infrastructure, tools, and preclinical models to support clinical studies in humans are being prepared. Building on the pioneering trials that are replacing the retinal pigment epithelium, it is expected that by the end of this decade first-in-human trials for the replacement of retinal neurons will be initiated.