Open AccessStereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species
Author(s) -
Michael Byrne,
Vinod Vathipadiekal,
Luciano H. Apponi,
Naoki Iwamoto,
Kandasamy Pachamuthu,
Kenneth Longo,
Fangjun Liu,
Richard Looby,
Lauren Norwood,
Anee Shah,
Juili Dilip Shelke,
Chikdu Shakti Shivalila,
Hailin Yang,
Yuan Yin,
Lankai Guo,
Keith Bowman,
Chandra Vargeese
Publication year - 2021
Publication title -
translational vision science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 21
ISSN - 2164-2591
DOI - 10.1167/tvst.10.1.23
Subject(s) - malat1 , oligonucleotide , in vivo , potency , ex vivo , pharmacology , in vitro , rna , biology , microbiology and biotechnology , chemistry , biochemistry , dna , long non coding rna , genetics , gene