Open AccessLECT2 Ameliorates Blood–Retinal Barrier Impairment Secondary to Diabetes Via Activation of the Tie2/Akt/mTOR Signaling Pathway
Author(s) -
Yuanjun Qin,
Ke Xiao,
Zhong Zheng,
Yin Zhao,
Yu Tian,
Xiaoxia Sun
Publication year - 2022
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.63.3.7
Subject(s) - occludin , pi3k/akt/mtor pathway , protein kinase b , retinal , western blot , chemistry , microbiology and biotechnology , retina , endothelial stem cell , blood–retinal barrier , vascular permeability , barrier function , streptozotocin , umbilical vein , tight junction , signal transduction , diabetic retinopathy , diabetes mellitus , biology , endocrinology , in vitro , biochemistry , neuroscience , gene