Open AccessFormation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction
Author(s) -
Cristina Escrevente,
Ana S. Falcão,
Michael J. Hall,
Mafalda LopesdaSilva,
Pedro Antas,
Miguel M. Mesquita,
Inês S. Ferreira,
Helena Cardoso,
Daniela Cabral de Oliveira,
Ana C. Fradinho,
Thomas Ciossek,
Paul Nicklin,
Clare E. Futter,
Sandra Tenreiro,
Miguel C. Seabra
Publication year - 2021
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.62.9.39
Subject(s) - lysosome , lipofuscin , retinal pigment epithelium , microbiology and biotechnology , cathepsin d , phagosome , cathepsin , flow cytometry , granule (geology) , biology , retina , retinal , chemistry , phagocytosis , biochemistry , neuroscience , enzyme , paleontology