Open AccessTargeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model
Author(s) -
Tine Van Bergen,
TjingTjing Hu,
Karis Little,
Lies De Groef,
Lieve Moons,
Alan W. Stitt,
Elke Vermassen,
Jean H.M. Feyen
Publication year - 2021
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.62.13.18
Subject(s) - retinal , inflammation , inner nuclear layer , retina , diabetes mellitus , medicine , blood–retinal barrier , outer nuclear layer , vascular permeability , diabetic retinopathy , streptozotocin , inner plexiform layer , kallikrein , endocrinology , chemistry , ophthalmology , biology , biochemistry , enzyme , neuroscience