Open AccessCCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection
Author(s) -
Steffani Fitzpatrick,
Robert N. Lausch,
Robert A. Barrington
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.19-27810
Subject(s) - adoptive cell transfer , c c chemokine receptor type 6 , t cell , biology , flow cytometry , t cell receptor , immunology , immune system , microbiology and biotechnology , chemokine , chemokine receptor
γδ T cells offer an important early immune defense against many different pathogens, both bacterial and viral. Herein, we examined the capacity of γδ T cell subsets to provide protection in the cornea against herpes simplex virus-1 (HSV-1).