The Interplay Between E-Cadherin, Connexin 43, and Zona Occludens 1 in Retinal Pigment Epithelial Cells | Zendy

Huiqian Bao | Zendy; Shuai Yang | Zendy; Hui Li | Zendy; Haipei Yao | Zendy; Yao Zhang | Zendy; Jingfa Zhang | Zendy; GuoTong Xu | Zendy; Haiying Jin | Zendy; Fang Wang | Zendy

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The Interplay Between E-Cadherin, Connexin 43, and Zona Occludens 1 in Retinal Pigment Epithelial Cells

Author(s) -

Huiqian Bao,

Shuai Yang,

Hui Li,

Haipei Yao,

Yao Zhang,

Jingfa Zhang,

GuoTong Xu,

Haiying Jin,

Fang Wang

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.19-27768

Subject(s) - connexin , microbiology and biotechnology , tight junction , cadherin , gene knockdown , cell junction , gap junction , biology , colocalization , retinal pigment epithelium , immunoprecipitation , retinal , cell , chemistry , cell culture , apoptosis , intracellular , biochemistry , genetics

Cell-cell contact in retinal pigment epithelium (RPE) involves adherent junctions, gap junctions, and tight junctions, which are primarily composed by E-cadherin, zona occludens 1 (ZO-1), and connexin 43, respectively. Here, we aimed to explore the relationship and interplay between these junction-associated proteins.

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