LncRNA PLCD3-OT1 Functions as a CeRNA to Prevent Age-Related Cataract by Sponging miR-224-5p and Regulating PLCD3 Expression | Zendy

Jing Xiang | Zendy; Qin Chen | Zendy; Lihua Kang | Zendy; Guowei Zhang | Zendy; Yong Wang | Zendy; Bai Qin | Zendy; Jian Wu | Zendy; Tianqiu Zhou | Zendy; Yongzhao Han | Zendy; Huaijin Guan | Zendy

Open Access

LncRNA PLCD3-OT1 Functions as a CeRNA to Prevent Age-Related Cataract by Sponging miR-224-5p and Regulating PLCD3 Expression

Author(s) -

Jing Xiang,

Qin Chen,

Lihua Kang,

Guowei Zhang,

Yong Wang,

Bai Qin,

Jian Wu,

Tianqiu Zhou,

Yongzhao Han,

Huaijin Guan

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.19-27211

Subject(s) - competing endogenous rna , gene knockdown , biology , viability assay , long non coding rna , propidium iodide , microrna , cell growth , cell , apoptosis , microbiology and biotechnology , cancer research , rna , programmed cell death , gene , genetics

Long noncoding RNAs (lncRNAs) are important in disease progression and cellular functions. This study aimed to conduct global lncRNA profiling and characterize the role of lncRNA 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 3-sence RNA 1 (PLCD3-OT1) in the progression of age-related cataract (ARC).

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