Lowered Decorin With Aberrant Extracellular Matrix Remodeling in Aqueous Humor and Tenon's Tissue From Primary Glaucoma Patients | Zendy

Sampath Nikhalashree | Zendy; Gayathree Karthikkeyan | Zendy; Ronnie George | Zendy; Shantha Balekudaru | Zendy; Lingam Vijaya | Zendy; Vineet Ratra | Zendy; Konerirajapuram Natarajan Sulochana | Zendy; Karunakaran Coral | Zendy

Open Access

Lowered Decorin With Aberrant Extracellular Matrix Remodeling in Aqueous Humor and Tenon's Tissue From Primary Glaucoma Patients

Author(s) -

Sampath Nikhalashree,

Gayathree Karthikkeyan,

Ronnie George,

Shantha Balekudaru,

Lingam Vijaya,

Vineet Ratra,

Konerirajapuram Natarajan Sulochana,

Karunakaran Coral

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.19-27091

Subject(s) - ctgf , lysyl oxidase , decorin , extracellular matrix , glaucoma , bleb (medicine) , aqueous humour , trabeculectomy , connective tissue , proliferative vitreoretinopathy , transforming growth factor , growth factor , transforming growth factor beta , medicine , ophthalmology , chemistry , pathology , endocrinology , intraocular pressure , retinal detachment , biochemistry , retinal , receptor , proteoglycan

To evaluate the inflammatory cytokine, growth factors, extracellular matrix (ECM) remodeling genes, profibrotic and antifibrotic molecules in patients undergoing glaucoma filtration surgery (GFS). Additionally, the effect of preoperative antiglaucoma medications (AGMs) and postoperative bleb status were related to these parameters.

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