Comparison of MicroRNA Expression in Tears of Normal Subjects and Sjögren Syndrome Patients | Zendy

Kwang Gi Kim | Zendy; Yeji Yeon | Zendy; Won June Lee | Zendy; Yong Un Shin | Zendy; Heeyoon Cho | Zendy; YoonKyoung Sung | Zendy; Du Roo Kim | Zendy; Han Woong Lim | Zendy; Min Ho Kang | Zendy

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Comparison of MicroRNA Expression in Tears of Normal Subjects and Sjögren Syndrome Patients

Author(s) -

Kwang Gi Kim,

Yeji Yeon,

Won June Lee,

Yong Un Shin,

Heeyoon Cho,

YoonKyoung Sung,

Du Roo Kim,

Han Woong Lim,

Min Ho Kang

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.19-27062

Subject(s) - tears , microrna , medicine , downregulation and upregulation , real time polymerase chain reaction , gastroenterology , immunology , biology , gene , genetics

Deregulated expression of several microRNAs (miRNAs) in sera or salivary glands of patients with Sjögren syndrome (SS) has been reported. However, none have investigated miRNAs in samples that can represent lacrimal glands. We compared the miRNAs expression in the tears of SS patients and healthy controls. Moreover, we investigated the correlation between miRNAs expression and ocular staining score (OSS).

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