Discovery and Validation of Circulating Hsa-miR-210-3p as a Potential Biomarker for Primary Open-Angle Glaucoma | Zendy

Yaoming Liu | Zendy; Yayi Wang | Zendy; Yang Chen | Zendy; Xiuli Fang | Zendy; Tao Wen | Zendy; Mian-li Xiao | Zendy; Shida Chen | Zendy; Xiulan Zhang | Zendy

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Discovery and Validation of Circulating Hsa-miR-210-3p as a Potential Biomarker for Primary Open-Angle Glaucoma

Author(s) -

Yaoming Liu,

Yayi Wang,

Yang Chen,

Xiuli Fang,

Tao Wen,

Mian-li Xiao,

Shida Chen,

Xiulan Zhang

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.19-26663

Subject(s) - open angle glaucoma , receiver operating characteristic , glaucoma , biomarker , medicine , microrna , nerve fiber layer , area under the curve , real time polymerase chain reaction , oncology , ophthalmology , bioinformatics , biology , gene , genetics

Blood-based examination tools for glaucoma diagnosis in clinical practice, which can be useful for screening patients when traditional ophthalmic examinations cannot be utilized, are not available thus far. This study aimed to identify circulating microRNAs (miRNAs) associated with primary open-angle glaucoma (POAG) and explore their utility as diagnostic markers.

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