Open AccessEffects of Lentivirus-Mediated C3 Expression on Trabecular Meshwork Cells and Intraocular Pressure
Author(s) -
Junkai Tan,
Ning Fan,
Ke Wang,
Bingkai Feng,
Ming Yang,
Liang Guo,
Yun Wang,
Xuejun Zhu,
Paul L. Kaufman,
Iok Hou Pang,
Xuyang Liu
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-24978
Subject(s) - green fluorescent protein , trabecular meshwork , intraocular pressure , in vivo , chemistry , fluorescence microscope , transfection , ex vivo , schlemm's canal , in vitro , microbiology and biotechnology , andrology , ophthalmology , biology , medicine , fluorescence , gene , biochemistry , physics , quantum mechanics
We evaluated the effects of lentivirus-mediated exoenzyme C3 transferase (C3) expression on cultured primary human trabecular meshwork (HTM) cells in vitro, and on rat intraocular pressure (IOP).