Open AccessEffect of Human Corneal Mesenchymal Stromal Cell-derived Exosomes on Corneal Epithelial Wound Healing
Author(s) -
Ravand Samaeekia,
Behnam Rabiee,
Ilham Putra,
Xiang Shen,
Young Jae Park,
Peiman Hematti,
Medi Eslani,
Ali R. Djalilian
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-24803
Subject(s) - microvesicles , wound healing , exosome , stromal cell , mesenchymal stem cell , corneal epithelium , microbiology and biotechnology , biology , cornea , immunology , cancer research , microrna , biochemistry , neuroscience , gene
Mesenchymal stromal cells (MSCs) have been used therapeutically to modulate inflammation and promote repair. Extracellular vesicles, including exosomes, have been identified as one of the important mediators. This study investigated the effect of human corneal MSC-derived exosomes on corneal epithelial wound healing.