Open AccessBinocular Summation in Postillumination Pupil Response Driven by Melanopsin-Containing Retinal Ganglion Cells
Author(s) -
Marija Zivcevska,
Alan Blakeman,
Shaobo Lei,
Herbert C. Goltz,
Agnes M. F. Wong
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-24639
Subject(s) - melanopsin , intrinsically photosensitive retinal ganglion cells , giant retinal ganglion cells , neuroscience , retinal , chemistry , retina , ophthalmology , biology , medicine , retinal ganglion cell , photopigment
To investigate how melanopsin-mediated intrinsically photosensitive retinal ganglion cell (ipRGC) signals are integrated binocularly using chromatic pupillometry. We hypothesized that if the melanopsin system is summative, there will be a greater postillumination pupillary response (PIPR) under binocular conditions after viewing bright blue light.