Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome | Zendy

Agnė Žiniauskaitė | Zendy; Symantas Ragauskas | Zendy; Jenni J. Hakkarainen | Zendy; Cadmus Rich | Zendy; Rudolf A. Baumgartner | Zendy; Giedrius Kalesnykas | Zendy; David S. Albers | Zendy; Simon Kaja | Zendy

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Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome

Author(s) -

Agnė Žiniauskaitė,

Symantas Ragauskas,

Jenni J. Hakkarainen,

Cadmus Rich,

Rudolf A. Baumgartner,

Giedrius Kalesnykas,

David S. Albers,

Simon Kaja

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-24432

Subject(s) - lacrimal gland , medicine , pathology , lacrimal apparatus , tears , infiltration (hvac) , goblet cell , harderian gland , rose bengal , meibomian gland , fluorescein , ophthalmology , conjunctiva , immunology , biology , epithelium , eyelid , physics , genetics , quantum mechanics , fluorescence , thermodynamics

To determine the efficacy of trabodenoson, an adenosine mimetic with highly selective adenosine A1 receptor binding properties, in a preclinical mouse model for dry-eye disease.

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