Open AccessDiquafosol Sodium Inhibits Apoptosis and Inflammation of Corneal Epithelial Cells Via Activation of Erk1/2 and RSK: In Vitro and In Vivo Dry Eye Model
Author(s) -
Jin Hyoung Park,
Seong-Ho Moon,
Dong Hyun Kang,
Hyun Jun Um,
Suk-Yun Kang,
Jae Yong Kim,
Hungwon Tchah
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22925
Subject(s) - dichlorofluorescein , apoptosis , chemistry , in vivo , tunel assay , reactive oxygen species , protein kinase b , microbiology and biotechnology , pharmacology , biochemistry , biology
To evaluate the effect of diquafosol on corneal epithelium in a dry eye model using Transwell culture and a scopolamine-induced dry eye rat model.