Activation of Dendritic Cells in Dry Eye Mouse Model
Author(s) -
Shinji Maruoka,
Muneo Inaba,
Nahoko Ogata
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22550
Subject(s) - lymph , cd86 , cervical lymph nodes , immunology , flow cytometry , subcutaneous injection , follicular dendritic cells , immune system , dendritic cell , medicine , interleukin 4 , lymph node , mixed lymphocyte reaction , t cell , pathology , antigen presenting cell , cancer , metastasis
The immune system plays a major role in the pathogenesis of dry eye diseases (DED), and dendritic cells (DCs) are known to be important initiators of acquired immunity. Thus, the purpose of this study was to determine the contribution of DCs to the development of DED.
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