Open AccessHumoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients
Author(s) -
Felix F. Reichel,
Tobias Peters,
Barbara Wilhelm,
Martin Biel,
Marius Ueffing,
Bernd Wissinger,
Karl Ulrich BartzSchmidt,
Reinhild Klein,
Stylianos Michalakis,
M. Dominik Fischer
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22494
Subject(s) - titer , immunosuppression , immune system , medicine , antibody titer , concomitant , humoral immunity , intravitreal administration , immunology , antibody , ophthalmology , retinal
To study longitudinal changes of anti-drug antibody (ADA) titers to recombinant adeno-associated virus serotype 8 (rAAV8) capsid epitopes in nonhuman primates (NHP) and patients.
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