Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA) | Zendy

Akiko Futakuchi | Zendy; Toshihiro Inoue | Zendy; Tomokazu Fujimoto | Zendy; Utako Kuroda | Zendy; Miyuki Inoue-Mochita | Zendy; Eri Takahashi | Zendy; Saori Ohira | Zendy; Hidenobu Tanihara | Zendy

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Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA)

Author(s) -

Akiko Futakuchi,

Toshihiro Inoue,

Tomokazu Fujimoto,

Utako Kuroda,

Miyuki Inoue-Mochita,

Eri Takahashi,

Saori Ohira,

Hidenobu Tanihara

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-21403

Subject(s) - angiogenesis , chemistry , extracellular matrix , microbiology and biotechnology , smad , wound healing , signal transduction , bleb (medicine) , cancer research , biology , immunology , glaucoma , trabeculectomy , neuroscience

Suberoylanilide hydroxamic acid (SAHA) has been shown to support the maintenance of experimental filtration blebs in animal models. This study was performed to investigate the molecular mechanisms underlying the bleb-maintaining effects of SAHA in modulating wound healing activities of conjunctival fibroblasts.

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