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HTRA1 and TGF-β1 Concentrations in the Aqueous Humor of Patients With Neovascular Age-Related Macular Degeneration
Author(s) -
Gian Marco Tosi,
Elena Caldi,
Giovanni Neri,
Elisabetta Nuti,
Davide Marigliani,
Stefano Baiocchi,
Claudio Traversi,
Gabriele Cevenini,
Antonio Tarantello,
Fiorella Fusco,
Federica Nardi,
Maurizio Orlandini,
Federico Galvagni
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20922
Subject(s) - macular degeneration , ranibizumab , medicine , choroidal neovascularization , neovascularization , ophthalmology , vascular endothelial growth factor a , vascular endothelial growth factor , transforming growth factor , endocrinology , vegf receptors , angiogenesis , bevacizumab , chemotherapy
The purpose of this study was to evaluate the expression of high-temperature requirement A serine peptidase 1 (HTRA1), TGF-β1, bone morphogenetic protein 4 (BMP4), growth differentiation factor 6 (GDF6), and VEGFA proteins in the aqueous humor of patients with naïve choroidal neovascularization (nCNV) secondary to AMD.

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