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A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients
Author(s) -
Teruhiko Hamanaka,
Masae Kimura,
Tetsuro Sakurai,
Nobuo Ishida,
Jun Yasuda,
Masao Nagasaki,
Naoki Nariai,
Atsushi Endo,
Kei Homma,
Fumiki Katsuoka,
Yoichi Matsubara,
Masayuki Yamamoto,
Nobuo Fuse
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20646
Subject(s) - trabecular meshwork , glaucoma , myocilin , trabeculectomy , medicine , ophthalmology , pathogenesis , pathology , open angle glaucoma , electron microscope , optics , physics
This study evaluated specific relationships between pathogenic mechanisms and genetic polymorphisms in primary open-angle glaucoma (POAG). We analyzed the morphologies of trabeculectomy specimens obtained from patients with familial POAG.

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