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The Effects of Nonporous Silica Nanoparticles on Cultured Human Keratocytes
Author(s) -
Bora Yim,
Joo-Hee Park,
Hyejoong Jeong,
Jinkee Hong,
Young Joo Shin,
Roy S. Chuck,
Choul Yong Park
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20603
Subject(s) - intracellular , autophagy , vacuole , cytotoxicity , viability assay , microbiology and biotechnology , vimentin , reactive oxygen species , lactate dehydrogenase , chemistry , pi3k/akt/mtor pathway , biophysics , apoptosis , in vitro , cytoplasm , biology , biochemistry , immunology , enzyme , immunohistochemistry
Silica nanoparticles (SiNPs) are promising carriers for ophthalmic drug delivery. In this study, we investigated the effect of various sizes of nonporous SiNPs on cultured human keratocytes.

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