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Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush
Author(s) -
Giuseppe Rovere,
Francisco M. NadalNicolás,
Paloma SobradoCalvo,
David GarcíaBernal,
María Paz VillegasPérez,
Manuel VidalSanz,
Marta AgudoBarriuso
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20425
Subject(s) - gliosis , retinal , glial fibrillary acidic protein , medicine , retina , optic nerve , ophthalmology , vimentin , intravitreal administration , nerve fiber layer , pharmacology , pathology , immunohistochemistry , biology , neuroscience
To study the effect of topical administration of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID), on retinal gliosis and levels of prostaglandin E2 (PGE2) after complete optic nerve crush (ONC).

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