Open AccessIL-17A Promotes RANTES Expression, But Not IL-16, in Orbital Fibroblasts Via CD40-CD40L Combination in Thyroid-Associated Ophthalmopathy
Author(s) -
Sijie Fang,
Yazhuo Huang,
Sisi Zhong,
Yidan Zhang,
Xingtong Liu,
Yang Wang,
Ping Gu,
Huifang Zhou,
Xianqun Fan
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20199
Subject(s) - cd40 , graves' ophthalmopathy , thyroid , medicine , cancer research , graves' disease , biology , genetics , cytotoxic t cell , in vitro
This present study aims to investigate the phenotype of IL-17A-producing T cells in thyroid-associated ophthalmopathy (TAO) and the role of IL-17A on RANTES and IL-16 expression in orbital fibroblasts (OFs) from TAO patients.
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