Molecular Mechanisms Mediating Antiangiogenic Action of the Urokinase Receptor-Derived Peptide UPARANT in Human Retinal Endothelial Cells | Zendy

Carla Motta | Zendy; Gabriella Lupo | Zendy; Dario Rusciano | Zendy; Melania Olivieri | Zendy; Liliana Lista | Zendy; Mario De Rosa | Zendy; Vincenzo Pavone | Zendy; Carmelina Daniela Anfuso | Zendy

Open Access

Molecular Mechanisms Mediating Antiangiogenic Action of the Urokinase Receptor-Derived Peptide UPARANT in Human Retinal Endothelial Cells

Author(s) -

Carla Motta,

Gabriella Lupo,

Dario Rusciano,

Melania Olivieri,

Liliana Lista,

Mario De Rosa,

Vincenzo Pavone,

Carmelina Daniela Anfuso

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-19909

Subject(s) - urokinase receptor , angiogenesis , vascular endothelial growth factor , microbiology and biotechnology , mapk/erk pathway , protein kinase b , receptor , signal transduction , endothelial stem cell , vascular endothelial growth factor a , biology , cancer research , chemistry , in vitro , biochemistry , vegf receptors

To investigate the molecular mechanisms of the antiangiogenic activity of UPARANT, an antagonist of the urokinase-type plasminogen activator receptor (uPAR), on primary human retinal endothelial cells (HREC) as a model of in vitro angiogenesis.

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