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Progression of Late-Onset Stargardt Disease
Author(s) -
Stanley Lambertus,
Moritz Lindner,
Nathalie M. Bax,
Matthias M. Mauschitz,
Jennifer Nadal,
Matthias Schmid,
Steffen Schmitz-Valckenberg,
Anneke I. den Hollander,
Bernhard H. F. Weber,
Frank G. Holz,
Gert Jan van der Wilt,
Monika Fleckenstein,
Carel B. Hoyng
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-19833
Subject(s) - stargardt disease , medicine , abca4 , atrophy , visual acuity , confidence interval , hazard ratio , ophthalmology , macular degeneration , pathology , phenotype , biochemistry , chemistry , gene
Identification of sensitive biomarkers is essential to determine potential effects of emerging therapeutic trials for Stargardt disease. This study aimed to describe the natural history of late-onset Stargardt, and demonstrates the accuracy of retinal pigment epithelium (RPE) atrophy progression as an outcome measure.

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