Open AccessDown-Regulation of RNA 3′-Terminal Phosphate Cyclase Attenuates Toll-Like Receptor 3-Mediated Axonal Loss in the Retina and Optic Nerve
Author(s) -
Shravan K. Chintala,
Naveena Daram
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-19799
Subject(s) - optic nerve , retina , microbiology and biotechnology , toll like receptor , chemistry , terminal (telecommunication) , receptor , neuroscience , anatomy , biology , biochemistry , computer science , telecommunications , innate immune system
To investigate the role of RNA 3'-terminal phosphate cyclase (Rtca) in Toll-like receptor 3 (TLR3)-mediated loss of retinal ganglion cells (RGCs) and their axons.
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