Generation of Retinal Ganglion Cells With Functional Axons From Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells
Author(s) -
Taku Tanaka,
Tadashi Yokoi,
Fuminobu Tamalu,
Shuichi Watanabe,
Sachiko Nishina,
Noriyuki Azuma
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-19166
Subject(s) - embryonic stem cell , embryoid body , biology , microbiology and biotechnology , induced pluripotent stem cell , retina , stem cell , retinal , retinal ganglion cell , neuroscience , anatomy , botany , genetics , gene
We previously generated self-induced retinal ganglion cells (RGCs) with functional axons from human induced pluripotent stem cells (hiPSCs). We investigated whether self-induced RGCs from mouse embryonic stem cells (mESCs) and induced pluripotent stem cells (miPSCs) are realized by the similar induction protocol.
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