In Vivo Fluorescence Retinal Imaging Following AAV2-Mediated Gene Delivery in the Rat Retina | Zendy

Joo Yong Lee | Zendy; Yoonha Hwang | Zendy; Ji Hyun Kim | Zendy; Yu Seun Kim | Zendy; Bok Kyoung Jung | Zendy; Pilhan Kim | Zendy; Heuiran Lee | Zendy

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In Vivo Fluorescence Retinal Imaging Following AAV2-Mediated Gene Delivery in the Rat Retina

Author(s) -

Joo Yong Lee,

Yoonha Hwang,

Ji Hyun Kim,

Yu Seun Kim,

Bok Kyoung Jung,

Pilhan Kim,

Heuiran Lee

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-18862

Subject(s) - green fluorescent protein , retinal , retina , nerve fiber layer , in vivo , intraperitoneal injection , ophthalmology , ganglion cell layer , optic nerve , genetic enhancement , retinal ganglion cell , intravitreal administration , pathology , preclinical imaging , microbiology and biotechnology , biology , medicine , pharmacology , gene , neuroscience , biochemistry

The purpose of this study was to evaluate longitudinal gene expression patterns by retinal imaging using a modified custom-built confocal laser-scanning microscope in experimental rats after intravitreal injection of recombinant adeno-associated virus 2 (rAAV2-green fluorescent protein [GFP]).

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