FTY720 Attenuates Retinal Inflammation and Protects Blood–Retinal Barrier in Diabetic Rats | Zendy

Lingling Fan | Zendy; Hua Yan | Zendy

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FTY720 Attenuates Retinal Inflammation and Protects Blood–Retinal Barrier in Diabetic Rats

Author(s) -

Lingling Fan,

Hua Yan

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-18658

Subject(s) - occludin , blood–retinal barrier , proinflammatory cytokine , diabetic retinopathy , evans blue , inflammation , retinal , cell adhesion molecule , streptozotocin , medicine , vascular permeability , intercellular adhesion molecule , diabetes mellitus , pharmacology , tight junction , blot , tumor necrosis factor alpha , endocrinology , immunology , cell adhesion , chemistry , cell , biology , microbiology and biotechnology , ophthalmology , biochemistry , gene

FTY720 has shown a protective effect in several diseases via inhibiting inflammation and decreasing vascular permeability. The purpose of this study was to assess the impact of FTY720 on inflammation and the blood-retinal barrier (BRB) in diabetic rats.

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